Antimalaria Activities of Several Active Compounds from Medicinal Plants

The growth and spread of resistance to all first-line antimalarial drugs used in the treatment of malaria today has caused many problems in eradicating malaria in various countries in the world. Researchers have begun to look for candidates for new antimalarial drug compounds derived from natural products that have been scientifically proven to have antimalarial activity. This is done to replace antimalarial drugs that are currently experiencing resistance. Some active compounds that have been successfully isolated from various plants, including curcumin, kaempferol, piperine, andrographolide, α-mangostin, catechin, luteolin and betulinic acid, have been scientifically tested to have antimalarial activity with different mechanisms of action.

Key words: Malaria, Antimalarial, Curcumin, Kaempferol, Piperine, Andrographolide, α-Mangostin, Catechin, Luteolin, Betulinic acid.